Fig. 4
From: ImiRP: a computational approach to microRNA target site mutation
The Sequence Mutation module. a The input sequence is divided into “mutationally independent” regions. User-specified target sites spaced less than 7 nucleotides apart are grouped into a single independent region and are annotated based on the positions of the first and last nucleotides of sites within the given region. b To reduce computational overhead, sites within a given independent region are mutated as a unit, while sites in other regions are unchanged