Fig. 5
From: Detection and tracking of overlapping cell nuclei for large scale mitosis analyses
Gaussian Mixture Model fit on cell images. Each row shows an image of cells and the corresponding GMM fit with 2 and 3 component. The first row shows an image with 2 cells while the second row shows an image with 3 cells. The 3-component model (1c and 2c) is always more accurate on any given image than the 2 component model (1b and 2b) but the fitting error difference between the two models can vary significantly. See fitting error Err on three cells of the 2-component model (2b). We take advantage of this variation over time to detect the transition between 2 cells and 3 cells whether they appear distinct as on this example or they overlap. Scalebar is 20 μ m