Gene signature-based mapping of immunological systems and diseases

BMC Bioinformatics

Table 2 Immune disease gene signatures

Disease category	# of gene set	# of study	# of signature disease gene
COPD	20	13	169
Asthma	20	10	11
Dermatitis	12	8	51
Psoriasis	7	5	161
IBD	19	8	100
Lupus	25	17	154
Arthritis	20	11	55
Sclerosis	13	7	1
T1D	19	8	15

“# of Gene set” indicates the number of gene sets for each disease category; “# of Study” indicates the number of independent studies that were analyzed to generate the gene sets; “# of Signature Disease Gene” indicates the number of genes existing in more than five gene sets from at least two different studies. COPD chronic obstructive pulmonary disease, IBD inflammatory bowel disease, T1D type 1 diabetes

ISSN: 1471-2105