Table 1 Summary of modified drug function for CYP2C19 by ethnicity in the 1000 genomes dataset exported from G-DOC Plus (rounded to the nearest decimal)
From: G-DOC Plus – an integrative bioinformatics platform for precision medicine
Phenotype (Drug metabolizer status) | Ad-mixed American (AMR) % | African (AFR) % | East Asian (ASN) % | European (EUR) % | South Asian (SAN) % |
|---|---|---|---|---|---|
UM (*17/*17)a | 2 | 6 | 0 | 5 | 0 |
UM or EM (*1/*17) | 16 | 23 | 2 | 29 | 0 |
EM | 55 | 35 | 31 | 38 | 0 |
IM | 23 | 22 | 54 | 19 | 0 |
PM (*2/*2, *2/*3, *3/*3) | 1 | 3 | 11 | 1 | 0 |
Not PM | 3 | 9 | 2 | 8 | 0 |
IM or PM | 0 | 1 | 0 | 0 | 0 |
Unknown/NA | 0 | 1 | 0 | 0 | 0 |
TOTAL % | 100 | 100 | 100 | 100 | 0 |