CyTRANSFINDER: a Cytoscape 3.3 plugin for three-component (TF, gene, miRNA) signal transduction pathway construction

Table 3 List of Double Indirect s. miRNA STPs obtained with CyTRANSFINDER using human miR-146a as the source intergenic miRNA, targets according to TargetScan 5.1 as destination genes and miRNA targets confirmed in at least two of the source databases

SmiRNA	References	TF	References	TF target (Gene)	ImiRNA	DG
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	MLL2
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	C10ORF76
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	PBX2
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	NF2
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	NPAS4
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	HIC2
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	LRTOMT
has-miR-146a	[37, 50–52]	SMAD4	[39]	POR	has-miR-4651	VAT1
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	GOSR1
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	SLC2A3
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	RNF4
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	SCN3B
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	GALNT10
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	MMP16
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	IER5L
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	GNL1
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	KIAA1274
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	KPNA6
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	NFASC
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	GGA2
has-miR-146a	[53]	BRCA1	[40, 54, 55]	CYP19A1	has-miR-4713	ADARB1

SmiRNA: Source intergenic miRNA; TF: Transcription Factor; TF target (Gene): Transcription Factor target gene, which is also the host gene for a miRNA; ImiRNA: miRNA located inside the TF target gene; DG: Destination Gene; Reference: data available from literature

ISSN: 1471-2105