From: Leveraging protein quaternary structure to identify oncogenic driver mutations
Quaternary only | Tertiary only | p-value | |||
---|---|---|---|---|---|
Method | Num structures | Num in OMIM | Num structures | Num in OMIM | |
iPAC | 56 | 42 (75 %) | 33 | 8 (24 %) | 4.49×10−6 |
GraphPAC | 43 | 31 (72 %) | 27 | 10 (37 %) | 4.04×10−3 |
SpacePAC | 21 | 11 (52 %) | 15 | 5 (33 %) | 0.214 |