Leveraging protein quaternary structure to identify oncogenic driver mutations

BMC Bioinformatics

Table 2 This table summarizes how many of the structures identified as having a significant cluster by one of the quaternary methodologies also had a subunit that had at least one damaging (in the case of Polyphen-2) or driver (in the case of CHASM) mutation

Column (1) specifies the quaternary methodology used and column (6) denotes how many total structures were flagged using that quaternary approach. Columns (3)-(5) break out the results by the specific machine learning approach

ISSN: 1471-2105