|
P-value |
---|
Structure | iPAC | GraphPAC | SpacePAC |
---|
2YDR | 1.89E-13 | 6.27E-18 | <0.001 |
1SUV | 2.39E-06 | 1.57E-05 | |
3W14 | 4.57E-06 | | |
1DTW | 5.22E-06 | | |
1U5B | 2.22E-05 | | |
3V8X | | 1.49E-05 | |
4MNQ | | 1.48E-04 | |
1QVO | | 1.60E-04 | <0.001 |
1I5K | | | <0.001 |
3B13 | | | <0.001 |
1A9W | | | 0.002 |
- A blank entry in position (i,j) denotes that methodology j did not find that structure to be statistically significant. We note that if a structure had n total mutations, then the pairwise methodologies of iPAC and GraphPAC calculate \(\frac {n(n-1)}{2}\) comparisons, one for each pair of mutations. Therefore, the p-values shown for iPAC and GraphPAC are shown post a Bonferroni correction. For SpacePAC, as 1000 simulations were run for each structure, the minimum possible p-value we can report is p<1.00E−03. Please see [26] for more details