Fig. 5From: Analysis of secondary structural elementsĀ in human microRNA hairpin precursorsAnalysis of bulges found in human miRNAs. (a) the occurrences of 5ā bulge Uās with different closing base pair combinations. (b) the number of 1-nucleotide 5ā bulges with different closing base pair combinations found in human miRNAĀ hairpin precursors. The most frequently occurring closing base pair combination was determined for each 1-nucleotide bulge, and then calculated for all others. Each closing base pair combination has a unique color, which is applied to each type of bulge. (c) the directionality of the motif (5ā bulge vs. 3ā bulge) influences preference of closing base pairs.Back to article page