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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Analysis of secondary structural elementsĀ in human microRNA hairpin precursors

Fig. 5

Analysis of bulges found in human miRNAs. (a) the occurrences of 5ā€™ bulge Uā€™s with different closing base pair combinations. (b) the number of 1-nucleotide 5ā€™ bulges with different closing base pair combinations found in human miRNAĀ hairpin precursors. The most frequently occurring closing base pair combination was determined for each 1-nucleotide bulge, and then calculated for all others. Each closing base pair combination has a unique color, which is applied to each type of bulge. (c) the directionality of the motif (5ā€™ bulge vs. 3ā€™ bulge) influences preference of closing base pairs.

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