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Table 1 Estimated parameters by DSLM

From: Computational modeling of phagocyte transmigration for foreign body responses to subcutaneous biomaterial implants in mice

Parameter

Description

Estimation

t 1

Starting time that the external source is released

3.5000

k e0

An initial concentration of the external source

11.2464

k k1

A self contraction of the external source

0.1017

β

An initial concentration of the oscillation bound

0.0134

k w0

An initial value of the oscillation frequency

1.4037

k k2

A contraction rate of the oscillation frequency

0.0937

k rhch

A rate that the residual histamine decayed

0.3704

k hs

A rate that the histamine regulates itself

0.0002

k hchrb

A rate that the histamine receptors are released

0.9997

k hchrt

A upper bound rate that the histamine receptors are released

0.0757

k hrs

A rate that the histamine receptors regulate themselves

0.7232

k hcsb

A lower bound of rate that the selectins are released

1.9997

k hcst

A upper bound of rate that the selectins are released

0.2668

k ss

A rate that the selectins regulate themselves

0.1024

k pmnipb

A lower bound of rate that increases the permeability for PMN

0.2226

k pmnipt

A upper bound of rate that increases the permeability for PMN

2.0000

k pmnps

A rate that the permeability of the capillary self degrades

0.1003

k mpipb

A lower bound of rate that increases the permeability for M Φ

0.0001

k mpipt

A upper bound of rate that increases the permeability for M Φ

1.0108

k mpps

A rate that the permeability of the capillary self degrades

0.1961

k pmns

A rate that the PMN self degrades

0.0582

k mps

A rate that the M Φ self degrades

0.0307