From: Sparse regressions for predicting and interpreting subcellular localization of multi-label proteins
Label | Subcellular location | LOOCV Locative Accuracy (LA) | |||
---|---|---|---|---|---|
iLoc-Hum [68] | mGOASVM [44] | mLASSO | mEN | ||
1 | Centrosome | 56/77 = 0.727 | 64/77 = 0.831 | 42/77 = 0.546 | 60/77 = 0.779 |
2 | Cytoplasm | 561/817 = 0.687 | 683/817 = 0.836 | 699/817 = 0.856 | 683/817 = 0.836 |
3 | Cytoskeleton | 27/79 = 0.342 | 44/79 = 0.557 | 29/79 = 0.367 | 32/79 = 0.405 |
4 | Endoplasmic reticulum | 166/229 = 0.725 | 193/229 = 0.843 | 194/229 = 0.847 | 190/229 = 0.830 |
5 | Endosome | 1/24 = 0.042 | 9/24 = 0.375 | 1/24 = 0.042 | 5/24 = 0.208 |
6 | Extracellular | 325/385 = 0.844 | 344/385 = 0.894 | 311/385 = 0.808 | 314/385 = 0.816 |
7 | Golgi apparatus | 99/161 = 0.615 | 131/161 = 0.814 | 118/161 = 0.733 | 128/161 = 0.795 |
8 | Lysosome | 56/77 = 0.727 | 71/77 = 0.922 | 62/77 = 0.805 | 74/77 = 0.961 |
9 | Microsome | 7/24 = 0.292 | 18/24 = 0.750 | 1/24 = 0.042 | 14/24 = 0.583 |
10 | Mitochondrion | 284/364 = 0.780 | 339/364 = 0.931 | 336/364 = 0.923 | 336/364 = 0.923 |
11 | Nucleus | 918/1021 = 0.899 | 931/1021 = 0.912 | 922/1021 = 0.903 | 923/1021 = 0.904 |
12 | Peroxisome | 20/47 = 0.426 | 43/47 = 0.915 | 34/47 = 0.723 | 39/47 = 0.830 |
13 | Plasma membrane | 277/354 = 0.783 | 288/354 = 0.814 | 267/354 = 0.754 | 266/354 = 0.751 |
14 | Synapse | 12/22 = 0.546 | 12/22 = 0.546 | 3/22 = 0.136 | 13/22 = 0.591 |
Overall Actual Accuracy (OAA) | 2118/3106 = 0.682 | 2251/3106 = 0.725 | 2265/3106 = 0.729 | 2307/3106 = 0.743 | |
Overall Locative Accuracy (OLA) | 2809/3681 = 0.763 | 3170/3681 = 0.861 | 3019/3681 = 0.820 | 3077/3681 = 0.836 | |
Accuracy | – | 0.821 | 0.814 | 0.827 | |
Precision | – | 0.851 | 0.859 | 0.869 | |
Recall | – | 0.888 | 0.857 | 0.870 | |
F1 | – | 0.853 | 0.843 | 0.855 | |
Micro F1 | – | 0.835 | 0.826 | 0.837 | |
Macro F1 | – | 0.740 | 0.638 | 0.741 | |
HL | – | 0.029 | 0.029 | 0.028 |