A two-layer integration framework for protein complex detection

BMC Bioinformatics

Table 1 Comparison between TINCD and state-of-the-art methods with respect to CYC2008

Methods	No. of complexes	No. of covered proteins	Acc	FRAC
TINCD	1562	5846	0.776	0.813
EC-BNMF	457	2105	0.751	0.677
CMBI	618	1041	0.459	0.349
InteHC	684	3400	0.748	0.634
CFinder	245	2008	0.518	0.319
CMC	562	1651	0.643	0.655
COACH	746	1838	0.650	0.664
ClusterONE	342	1366	0.584	0.438
DPClus	651	2140	0.639	0.680
IPCA	816	1621	0.617	0.575
MCL	600	4101	0.644	0.536
MCODE	108	666	0.485	0.311
RNSC	541	2095	0.619	0.506
RRW	248	1174	0.571	0.511
SPICi	412	2113	0.607	0.502
BT	409	1286	0.728	0.591
C2S	1035	4500	0.761	0.664
CACHET	449	964	0.674	0.553
Hart	390	1307	0.720	0.600
Pu	400	1504	0.732	0.579

ISSN: 1471-2105