Fig. 2

Illustration of methylation data. Different to all other analyses types for methylation data the global view is just provided for one cancer entity at a time, due to the fact that the gene is partitioned into different regions. a Provides a global profile of the methylation status in SFRP1 and SFRP4 in COAD, where SFRP1s is highly differential methylated in its body region and SFRP4, as control, remains mostly unmethylated. Further, b and c give an estimate of the differential methylation distribution, which also allows the detection of shifts. The x-axis shows difference of the ß-values of the methylation status between tumor and normal samples. The y-axis reflects the number of samples