Fig. 6

Plaid plots of putative DIs detected in real data. Each “pixel” represents a box in the interaction space with sides of 100 kbp, where the colour of the pixel is proportional to the number of read pairs counted into that box. Putative DIs were defined as 1 Mbp bin pairs detected at a FDR of 5 %. The red rectangle marks the interaction space corresponding to the detected bin pair, in the Rickman et al. data set [5] between ERG- (a) and GFP-overexpressing prostate cells (b); in the Dixon et al. data set [4] between ESCs (c) and lung cells (d); and in the Sofueva et al. data set [16] between wild-type (e) and Rad21-knockout cells (f). All coordinates are shown in Mbp. Colours are also adjusted to account for differences in library size