Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments

BMC Bioinformatics

Table 1 Operating characteristics in simulation study of ρ = 0.1, 0.5 and 0.9.

Corr. Coef.	Method	Sensitivity	Specificity	PPV	NPV	FDR
0.1	GLRT	0.742	0.998	0.960	0.987	0.040
	LNN	0.667	0.991	0.826	0.980	0.174
	t-test	0.557	0.987	0.692	0.978	0.308
	fold change	0.309	0.999	0.968	0.966	0.032
0.5	GLRT	0.945	0.998	0.966	0.997	0.034
	LNN	0.635	0.986	0.873	0.972	0.127
	t-test	0.516	0.968	0.435	0.977	0.565
	fold-change	0.252	1	1	0.966	0
0.9	GLRT	0.980	0.999	0.990	0.999	0.010
	LNN	0.568	0.988	0.877	0.987	0.123
	t-test	0.406	0.972	0.436	0.969	0.564
	fold change	0.139	1	1	0.956	0

ISSN: 1471-2105