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Figure 1 | BMC Bioinformatics

Figure 1

From: SCOWLP classification: Structural comparison and analysis of protein binding regions

Figure 1

Schematic overview of the methodology. A) The contacting domains per family are extracted from the SCOWLP database. The Si are calculated for all-against-all contacting domains and used for clustering. Results are displayed in a dendrogram. B) Classification of protein binding regions (PBRs). A protein family can recognize other proteins and ligands by single- or multi-binding regions, and for each binding region single- or multi-interfaces may exist depending on the number of partners that have been structurally observed interacting within a specific binding region.

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