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Table 2 Performance of SVM classifiers trained with RBF kernel and features based on Amino Acid Composition, PSI-BLAST, PSSM-Profiles and Cascade SVM.

From: VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens

Classifier/training features

Sensitivity (%)

Specificity (%)

Accuracy (%)

MCC

AAC (A)

70.0

74.1

72.1

0.44

Dipeptide Composition(i+1 st ) (B)

70.0

72.3

71.1

0.42

Dipeptide Composition (i+2 nd ) (C)

70.2

73.7

72.0

0.44

Hybrid1 (A+B+C)

72.6

75.1

73.9

0.48

PSI-BLAST search (D)

52.5

51.7

52.1

----

Hybrid2 (A+B+C+D)

79.2

78.8

79.0

0.58

PSSM (E)

78.1

78.1

78.1

0.56

Hybrid3 (A+B+C+D+E)

79.0

80.1

79.6

0.59

Cascade (A+B+C+D+E)

82.0

81.5

81.8

0.64