Figure 1From: Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene expression signaturesNarrowing down existing gene signature to few genes. 23 human medulloblastoma expression profiles implemented by Affymetrix G110 cancer arrays were used [16]. Among them, 10 were metastatic tumours and 13 were non-metastatic tumours. This plot illustrates how users can filtrate out a handful of genes for diagnostic purpose by applying SET. The left panel is the heat map of the original signature [16], and arrows indicate mis-grouped samples. The middle panel shows two figures produced by SET (see Figure 2 for more details). The right panel is the heat map of the filtrated 4 new diagnostic markers.Back to article page