Figure 1From: Microarray-based gene set analysis: a comparison of current methodsDetection rates in simulated data sets as a function of increasing correlation. For each gene set analysis method, the data were permuted 2,000 times to generate p-values for each gene set, within each simulation. FDR-adjusted p-values of less than 0.05 were used to indicate significance. (a) Gene sets active in one class and inactive in the other, On-Off (D), with a difference between the means of 1. (b) Gene sets active in both classes, On-On (D), with a difference between the means of 1. (c) Gene sets active in one class and inactive in the other, On-Off (D), with a difference between the means of 0.5. (d) Gene sets active in both classes, On-On (D), with a difference between the means of 0.5.Back to article page