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Figure 1 | BMC Bioinformatics

Figure 1

From: Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation

Figure 1

Distribution of motifs in promoters bound by different TFs. The x axis represents the distance to the start codon and the y axis the fraction of promoter sequences containing the motif of interest. The red and blue lines show the distribution of the two orientations of the motif. The two top lines (with triangles) show motif distribution in the set of promoters bound by the TF and the two lines at the bottom (with circles) show the distribution in the control set. The following motif-experiment pairs are shown: A) the Abf1 motif (cgtn{6}tga) in promoters bound by Abf1 on YPD, B) the Rap1 motif (ccrtaca) in promoters bound by Rap1 on YPD, C) the Gcn4 motif (gagtca) in promoters bound by Gcn4 on YPD, D) the Mbp1 motif in promoters bound by Mbp1 on YPD, E) the Gal4 motitf (cggn{11}ccg) in promoters bound by Gal4 on galactose. The corresponding p-values for location bias and orientation bias are shown in Table 2.

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BMC Bioinformatics

ISSN: 1471-2105

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