Skip to main content

Table 2 Top 10 most frequently selected coregulators for the 368 verified MYC targets using different methods.

From: Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual information

Method

MI3

dMI3

BN

MI2

Rank\R2

Symbol

Targets

Symbol

Targets

Symbol

Targets

Symbol

Targets

1

ARPC1B

45

PSIP1

46

HAT1

23

CTPS

29

2

TRIP12

45

FNBP1

42

GTF2A2

15

JTV1

24

3

ASH2L

41

MRPL28

28

PSMD14

14

MRPL3

23

4

GCN5L2

35

RAB33A

23

PSMA4

13

SSRP1

21

5

SHOC2

25

HSPB1

22

SFRS1

13

TPX2

20

6

CSK

23

TPP2

21

PSMA3

12

PSMB7

19

7

ZNF143

23

ANKMY2

18

ADRM1

11

RFC4

19

8

FNBP1

22

CD59

18

DNMT1

10

MCM7

18

9

MIZF

22

KIAA0922

17

CCT5

10

HAT1

18

10

CBX1

19

SIAH2

17

WDR62

10

HSPC111

17

  1. Top 5 highest scoring cofactors are counted for each target. Cofactors in bold font are involved in MYC dependent or general transcriptional regulation, those in italics are in the list of 368 verified MYC targets with I(T; MYC) ≥ 0.3.