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Figure 6 | BMC Bioinformatics

Figure 6

From: Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual information

Figure 6

The transcriptional regulatory networks centered at MYC transcription factor. Networks included the top 10 most frequently selected MYC cofactors by using MI3 or control methods and the corresponding target genes (transparent). (a-d) are networks inferred by MI3, dMI3, BN and MI2 respectively. Regulators are large nodes and targets are small transparent nodes. Node colors indicate the identity where yellow is MYC, aquamarine are the cofactors involved in MYC dependent or general transcriptional regulation according to literature, gray are unverified cofactors, pink are confounding cofactors that are actually verified MYC targets. Edges represent transcription regulation. Note that all edges from MYC to targets are hidden for clarity.

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