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Figure 9 | BMC Bioinformatics

Figure 9

From: Evaluation of phylogenetic footprint discovery for predicting bacterial cis-regulatory elements and revealing their evolution

Figure 9

Partial divergence between the motifs discovered in lexA promoters of Gram-positive bacteria (Firmicutes and Actinobacteria). (A) Comparison between the significance scores of all discovered patterns in Actinobacteria and Firmicutes. The significance is arbitrarily set to -1 for non significant patterns (sig < 0), in order to highlight dyads detected in only one of the subgroups. (B) Sequence logo of motifs obtained by aligning all the sites annotated for Gram-positive bacteria (top), Firmicutes (middle) and Actinobacteria (bottom), respectively. For each taxon, all sites matching the discovered patterns were extracted with their flanking region and were aligned using MEME [3] with a motif width of 24 nucleotides. Sequence logos were generated with Weblogo [81]. (C) Feature-map of the dyads discovered in Gram-positive bacteria. The 17 first top sequences are promoters of sequences from Actinobacteria, while others are from Firmicutes. In Actinobacteria, the 11 first sequences are promoters of orthologous sequences from Corynebacterineae.

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