Figure 3
From: Prioritization of gene regulatory interactions from large-scale modules in yeast
Alignment of 4 orthologous 1 kb promoter regions for CIS3 and TF binding sites. We show only the region (-636 to -669 upstream of the TSS) which contains conserved binding sites for all predicted regulators (Swi6, Fkh2 and Ndd1). We used the six-species alignment from SGD (including S. mikatae, S. paradoxus and S. kudriavzevii), but removed from the SGD output S. castellii which is more distant, and S. bayanus which has a small intergenic region of only 30 nucleotides. Consensus motifs of the TFs from Harbison et al. are shown in the box using the IUPAC code. We denote degenerate binding sites of Swi4 and Mcm1 in blue. See the main text for more details.