Figure 4From: Extending pathways based on gene lists using InterPro domain signaturesSensitivity and specificity. Expected sensitivity (left) and specificity (right) of our method estimated through simulation of 100 sampled gene lists containing genes of varying numbers of KEGG pathways. 5 genes were sampled from each of 3, 5 or 10 different pathways, respectively, plus additional 50 random noise genes were added each time. The sensitivity and specificity was above 90% in all cases, the sampling variance indicated by the error bars is negligible.Back to article page