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Table 5 Top 20 domains that overlapped with indels.

From: Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins

Domain ID (Pfam)

Domain Name

# of proteins with the domain overlapping with an indel

Total # of proteins with the domain

Domain fraction

P-value (one tail) from Fisher's exact test

PF00141

Peroxidase

88

88

1

1.85E-26

PF00565

Staphylococcal nuclease homologue

44

44

1

1.42E-13

PF02876

Staphylococcal/Streptococcal toxin, beta-grasp domain

33

33

1

2.33E-10

PF02898

Nitric oxide synthase, oxygenase domain

31

31

1

8.94E-10

PF00199

Catalase

30

30

1

1.75E-09

PF00232

Glycosyl hydrolase family 1

30

30

1

1.75E-09

PF00502

Phycobilisome protein

29

29

1

3.43E-09

PF01327

Polypeptide deformylase

24

24

1

9.92E-08

PF00896

Phosphorylase family 2

23

23

1

1.94E-07

PF00490

Delta-aminolevulinic acid dehydratase

22

22

1

3.81E-07

PF01742

Clostridial neurotoxin zinc protease

21

21

1

7.45E-07

PF00022

Actin

20

20

1

1.46E-06

PF00274

Fructose-bisphosphate aldolase class-I

20

20

1

1.46E-06

PF00503

G-protein alpha subunit

20

20

1

1.46E-06

PF00224

Pyruvate kinase, barrel domain

17

17

1

1.10E-05

PF03414

Glycosyltransferase family 6

16

16

1

2.15E-05

PF00217

ATP:guanido phosphotransferase, C-terminal catalytic domain

15

15

1

4.21E-05

PF00343

Carbohydrate phosphorylase

15

15

1

4.21E-05

PF00113

Enolase, C-terminal TIM barrel domain

14

14

1

8.24E-05

PF00162

Phosphoglycerate kinase

13

13

1

1.61E-04