Table 2 Probe sets associated with the 5 most significant mRNA changes in mice and whose human ortholog showed significant same-sign regulation (i.e. concordant, A) or significant different-sign regulation (i.e. discordant, B). PS, GS, logFC and P stand for probe set, gene symbol, log₂ fold change and p-value respectively. P-values in the human dataset (last column) are Bonferroni-corrected to adjust for multiple testing (44'928 human probe sets in total).

93273_at

Snca

-0.53

6.8E-04

204467_s_at

SNCA

-0.42

6.8E-05

96497_s_at

Myt1l

-1.03

8.0E-04

210016_at

MYT1L

-1.53

1.8E-04

99511_at

Prkcb

-1.02

8.6E-04

209685_s_at

PRKCB1

-1.27

2.7E-05

102711_at

Rgs14

-0.76

1.0E-03

211021_s_at

RGS14

-1.07

1.7E-08

104678_at

Gas7

-0.35

1.9E-03

202192_s_at

GAS7

-0.58

8.1E-05

B: discordant

mouse PS

mouse GS

mouse logFC

mouse P

human PS

human GS

human logFC

human corrected P

102704_at

Aqp4

-0.99

3.3E-03

210068_s_at

AQP4

0.84

4.9E-02

102299_at

Prkca

-0.38

6.8E-03

213093_at

PRKCA

0.34

3.2E-02

100003_at

Ryr1

-0.63

6.8E-03

205485_at

RYR1

0.59

9.6E-04

100888_at

Sorl1

-0.37

9.5E-03

203509_at

SORL1

0.50

3.0E-04

99367_at

5530600P05Rik

-0.29

1.2E-02

200713_s_at

MAPRE1

0.43

1.6E-03