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Table 2 Results for rds01 using the new method.

From: A simple and robust method for connecting small-molecule drugs using gene-expression signatures

Rank

Compound

ID

score

pvalue

1

(-)-catechin

1101

0.334

0.003

2

sirolimus

1022

0.312

0.006

3

phentolamine

1138

0.309

0.007

4

5162773

892

0.292

0.011

5

resveratrol

595

0.286

0.013

...

...

...

...

 

451

felodipine

848

-0.002

0.988

452

estradiol

988

-0.001

0.991

453

bucladesine

959

0.001

0.993

  1. The connection scores for the random gene signature rds01 using the new method. To control the expected number of false connections at 1, the threshold p value was set at 1/453 = 0.0022. No connection was found to be significant, which agrees with the known truth.
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BMC Bioinformatics

ISSN: 1471-2105

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