Figure 2From: From biophysics to evolutionary genetics: statistical aspects of gene regulationThermodynamic states of a transcription factor. (1) Unbound state, with three-dimensional diffusion. (2) Unspecific bound state, with one-dimensional diffusion along the DNA backbone. (3) Specific bound state. The binding energy depends on the genotype at the binding locus, which has length â„“ and whose position is specified by the coordinate r.Back to article page