Table 1 Genes used in model construction.
Gene Symbol | Accession Number | GeneID | Gene Description | Function |
|---|---|---|---|---|
GPC3 | NM_004484 | 2719 | glypican 3 | Cell surface heparan sulfate proteoglycans; may play a role in the control of cell division and growth regulation |
RASSF1A | NM_007182 | 11186 | Ras association domain family 1 | Protein similar to the RAS effector proteins; interact with DNA repair protein XPA; inhibit cyclin D1 accumulation thereby inducing cell cycle arrest |
WT1 | NM_000378 | 7490 | Wilms tumor 1 | A transcription factor; mutated in a small subset of patients with Wilm's tumours |
PLAU | NM_002658 | 5328 | plasminogen activator, urokinase | A serine protease involved in degradation of the extracellular matrix. |
HOXA5 | NM_019102 | 3202 | homeobox | A DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. |
CDKN2A | NM_000077 | 1029 | cyclin-dependent kniase inhibitor 2A | Functions as a stabilizer of the tumor suppressor protein p53. |
HS3ST3B1 | NM_006041 | 9953 | heparan sulfate 3-O-sulfotransferase 3B1 | An enzyme that possesses heparan sulfate glu-cosaminyl 3-O-sulfotransferase activity |
BRCA1 | NM_007294 | 672 | breast cancer 1, early onset | A nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor |
DAPK1 | NM_004938 | 1612 | death-associated protein kinase 1 | A positive mediator of gamma-interferon induced programmed cell death |