Figure 4
From: A replica exchange Monte Carlo algorithm for protein folding in the HP model
Comparison of the distribution of H-H contact orders found by REMC, ACO-HPPFP-3 and PERM. The frequency distribution of relative contact order values for folding S1-7 in 2D (left side) and S2-5 in 3D (right side) over 500 independent runs is shown. This measure can be employed to compare the quantity and diversity of folds returned by one or more algorithms. In both the 2D and 3D case, REMC variants have a more even distribution and find a larger number of relative contact order values than PERM or ACO-HPPFP-3. REMC and ACO-HPPFP-3 both find relative contact orders larger than PERM in 2D. In 3D, REMC finds larger relative contact order values than both PERM and ACO-HPPFP-3.