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Figure 11 | BMC Bioinformatics

Figure 11

From: The topology of metabolic isotope labeling networks

Figure 11

Workflow of an isotope-based MFA. After the evaluation of a real ILE measurement data is available for the mathematical modeling. Initially starting with a guess on the flux values, a simulation of the ILE aims to reproduce the measurement data. A parameter fitting procedure is used to obtain an estimation of the real flux values by gradual variation.

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