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Table 2 Comparison of SNR and S value of predicted datasets before (raw data) and after (filtered data) removing false positive protein-protein interaction pairs

From: False positive reduction in protein-protein interaction predictions using gene ontology annotations

  Yeast Worm
Method SNR* (raw data) SNR* (filtered data) S SNR* (raw data) SNR* (filtered data) S
PP 1.59 15.78 9.90 32.78 129.0 3.94
GE 1.89 8.83 4.67 27.36 66.0 2.41
CC 3.10 12.21 3.94 51.88 202.0 3.89
MLE 13.44 31.14 2.32 197.2 387.0 1.96
  1. *SNR was calculated based on Equation (7). The size of the random dataset was the same as that of protein pairs predicted by each respective method and their true positive fractions were obtained using the mean of 100 trials.