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Table 2 Comparison of SNR and S value of predicted datasets before (raw data) and after (filtered data) removing false positive protein-protein interaction pairs

From: False positive reduction in protein-protein interaction predictions using gene ontology annotations

 

Yeast

Worm

Method

SNR* (raw data)

SNR* (filtered data)

S

SNR* (raw data)

SNR* (filtered data)

S

PP

1.59

15.78

9.90

32.78

129.0

3.94

GE

1.89

8.83

4.67

27.36

66.0

2.41

CC

3.10

12.21

3.94

51.88

202.0

3.89

MLE

13.44

31.14

2.32

197.2

387.0

1.96

  1. *SNR was calculated based on Equation (7). The size of the random dataset was the same as that of protein pairs predicted by each respective method and their true positive fractions were obtained using the mean of 100 trials.
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BMC Bioinformatics

ISSN: 1471-2105

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