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Table 1 NN performance. The results given in this table illustrate the ability of the trained NN, which are at the core of our method, to distinguish between correct from incorrect pairs of AS homologous events. The results in the second column correspond to the cross-validated performance of NN when tested using 473 and 4746 correct and incorrect pairs of homologous AS events, respectively. The results in the third column were obtained after replacing the 4746 incorrect pairs with a small set of 86 of hard-to-identify incorrect pairs. In both cases NN was shown to have a good recognition ability.

From: A procedure for identifying homologous alternative splicing events

 

True positives + Built negative cases

True positives + Hard negative cases

Accuracy

0.89 ± 0.01

0.82 ± 0.02

Precision

0.46 ± 0.06

0.83 ± 0.01

Sensitivity

0.94 ± 0.02

0.94 ± 0.02

Specificity

0.88 ± 0.01

0.47 ± 0.05