Table 1 Residue compositions of four protein datasets. The values are means and standard deviations of relative frequencies obtained in 100,000 bootstrap sampling iterations

Ala (A)

7.89 ± 0.05

7.70 ± 0.08

6.03 ± 0.13

8.10 ± 0.35

Arg (R)

5.40 ± 0.04

4.93 ± 0.06

6.56 ± 0.13

4.82 ± 0.23

Asn (N)

4.13 ± 0.04

4.58 ± 0.06

6.23 ± 0.15

3.82 ± 0.27

Asp (D)

5.35 ± 0.03

5.83 ± 0.05

8.18 ± 0.10

5.80 ± 0.30

Cys (C)

1.50 ± 0.02

1.74 ± 0.05

0.78 ± 0.04

0.80 ± 0.08

Gln (Q)

3.95 ± 0.03

3.95 ± 0.05

5.21 ± 0.09

5.27 ± 0.37

Glu (E)

6.67 ± 0.04

6.65 ± 0.07

8.70 ± 0.17

9.89 ± 0.61

Gly (G)

6.96 ± 0.04

7.16 ± 0.07

7.06 ± 0.11

7.41 ± 0.40

His (H)

2.29 ± 0.02

2.41 ± 0.04

2.60 ± 0.06

1.93 ± 0.11

Ile (I)

5.90 ± 0.04

5.61 ± 0.06

2.77 ± 0.07

3.24 ± 0.13

Leu (L)

9.65 ± 0.04

8.68 ± 0.08

5.11 ± 0.08

6.22 ± 0.25

Lys (K)

5.92 ± 0.05

6.37 ± 0.08

9.75 ± 0.16

7.85 ± 0.45

Met (M)

2.38 ± 0.02

2.22 ± 0.04

1.13 ± 0.04

1.87 ± 0.10

Phe (F)

3.96 ± 0.03

3.98 ± 0.04

2.38 ± 0.05

2.44 ± 0.13

Pro (P)

4.83 ± 0.03

4.57 ± 0.05

5.63 ± 0.10

8.11 ± 0.63

Ser (S)

6.83 ± 0.04

6.19 ± 0.06

6.87 ± 0.13

8.65 ± 0.43

Thr (T)

5.41 ± 0.02

5.63 ± 0.05

6.08 ± 0.11

5.56 ± 0.24

Trp (W)

1.13 ± 0.01

1.44 ± 0.03

1.33 ± 0.05

0.67 ± 0.06

Tyr (Y)

3.03 ± 0.02

3.50 ± 0.04

3.58 ± 0.08

2.13 ± 0.15

Val (V)

6.73 ± 0.03

6.72 ± 0.06

4.01 ± 0.06

5.41 ± 0.44