Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector machine approach

Table 4 Distribution of different classes of metal-binding proteins (calcium-binding, magnesium-binding, iron-binding, and zinc-binding) in different kingdoms and in top 10 host species. Not all protein sequences studied in this work are included because the host species information of some protein sequences is not yet available in the protein sequence database

	Calcium-binding		Magnesium-binding		Iron-binding		Zinc-binding
	Kingdom or species	No. of proteins	Kingdom or species	No. of proteins	Kingdom or species	No. of proteins	Kingdom or species	No. of proteins
Protein distribution in kingdom	Archaea	73	Archaea	262	Archaea	381	Archaea	1048
	Bacteria	1092	Bacteria	2597	Bacteria	3743	Bacteria	6916
	Eukaryota	3897	Eukaryota	1081	Eukaryota	5248	Eukaryota	6464
	Viridae	343	Viridae	194	Viridae	29	Viridae	1466
Protein distribution in top 10 species	Homo sapiens	651	Homo sapiens	140	Arabidopsis thaliana	278	Homo sapiens	1121
	Mus musculus	499	Mus musculus	129	Escherichia coli	214	Mus musculus	911
	Rattus norvegicus	305	Arabidopsis thaliana	117	Homo sapiens	191	Rattus norvegicus	382
	Arabidopsis thaliana	186	Rattus norvegicus	69	Mus musculus	185	Saccharomyces cerevisiae	380
	Bos taurus	142	Escherichia coli	63	Rattus norvegicus	152	Arabidopsis thaliana	359
	Gallus gallus	103	Saccharomyces cerevisiae	55	Drosophila melanogaster	124	Caenorhabditis elegans	255
	Drosophila melanogaster	94	Bacillus subtilis	53	Methanococcus jannaschii	92	Drosophila melanogaster	237
	Oryctolagus cuniculus	82	Escherichia coli O157:H7	45	Saccharomyces cerevisiae	88	Schizosaccharomyces pombe	221
	Sus scrofa	65	Salmonella typhimurium	44	Escherichia coli O157:H7	87	Escherichia coli	172
	Caenorhabditis elegans	64	Schizosaccharomyces pombe	43	Bacillus subtilis	77	Methanococcus jannaschii	119

ISSN: 1471-2105