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Figure 1 | BMC Bioinformatics

Figure 1

From: SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks

Figure 1

SigFlux , connectivity and the clustering coefficient of mouse proteins in different phenotype groups. Mutant phenotypes of genes in mouse are grouped into the following 3 categories: group 1 corresponds to no obvious phenotype, group 2 is a viable phenotype, and group 3 is a lethal phenotype, as shown on the x-axis. The median and standard deviation of SigFlux, connectivity and the clustering coefficient in different groups are shown on the y-axis, respectively. (a) A positive correlation exists between SigFlux and essentiality. (b) A positive correlation exists between connectivity and essentiality. (c) No obvious correlation exists between the clustering coefficient and essentiality.

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