Skip to main content

Table 2 Predictive results obtained by using different similarity measures for GO term pairs

From: Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction

Semantic similarity method

Lord

SimLP

Exact Match

Compartment

MCC (Accuracy %)

PML BODY

0.223 (31.6)

0.253 (34.2)

0.250 (31.6)

Nuclear Lamina

0.579 (60.0)

0.578 (63.6)

0.578 (63.6)

Nuclear Splicing Speckles

0.598 (66.1)

0.607 (62.5)

0.63 (62.5)

Chromatin

0.511 (59.0)

0.518 (60.7)

0.509 (57.4)

Nucleoplasm

0.411 (50.7)

0.504 (56.0)

0.483 (54.7)

Nucleolus

0.615 (75.3)

0.656 (79.0)

0.642 (80.8)

Overall for Single-localization

0.489 (63.7)

0.519 (66.5)

0.515(66.5)

  1. (Based on SUM_Match: The similarity of two proteins is defined as the sum of similarity scores over all matched GO term pairs.)