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Table 3 The numbers of predicted domain interactions using domain fusion, domain function, and combining six data sets. The predicted domain interactions, the number of evidences, and the overlaps with iPfam. Numbers in the first column indicate the number of evidences for the domain interactions, and the second column is the number of interactions having the corresponding evidences. "PPI" represents the protein interaction data sets. "Fraction" indicates the fraction of domain interactions in iPfam in a given set. "Fold" indicates the ratio of the fraction over expected value (0.17%).

From: An integrated approach to the prediction of domain-domain interactions

Evidence Interactions Overlap with iPfam Fraction Fold
Random domain pairs 1,539,135 2,580 0.17% -
Domain fusion 9,615 1,141 11.8% 69
Domain fusion & PPI 859 283 32.9% 194
Same GO terms 57,907 1,302 0.8% 13
Same GO terms & PPI 1,031 234 22.7% 134
≥ 1 23,606 2,071 8.8% 52
≥ 2 1,624 820 50.5% 297
≥ 3 307 200 65.1% 383
≥ 4 58 43 74.1% 436
≥ 5 13 10 76.9% 452
= 6 0 - - -