Figure 1

Performance of PhyloCon, Converge, and the combined motif set on data for factors of known specificity. PhyloCon and Converge both recover more true positives than the suite of 6 programs employed in Harbison et al. Combining the results of PhyloCon and Converge significantly increases the number of true positives recovered, and eliminates false negatives, without a large adverse effect on the false positive rate. For definitions of the scoring criteria, see the Methods section.