Figure 3
From: Metabolite coupling in genome-scale metabolic networks
The distribution of metabolite coupling in E. coli. The number of metabolite pairs that occur together in each possible number of reactions is plotted on a log-log scale. There are many metabolite pairs that never occur together, and there are many particular numbers of reactions in which no metabolite pairs occur, but these are not shown because zero does not appear on a log-log plot. The points and most coupled metabolite pairs are colored to improve clarity and readability, but they are all in the E. coli network. The top four metabolite pairs, located at the right of the figure, all occur in over 100 reactions together.