Table 2 Analysis of InterPro domain composition in clusters calculated for SwissProt database
K | cases | clusters | true positive | false positive | false negative | specificity | a posteriori sensitivity | a priori sensitivity |
|---|---|---|---|---|---|---|---|---|
SPC | ||||||||
2 | 18960 | 4423 | 39414 | 1239 | 988 | 96.7 | 97.6 | 16.7 |
6 | 78441 | 11418 | 159201 | 6045 | 8474 | 96.3 | 94.9 | 67.6 |
20 | 96716 | 6635 | 185012 | 11514 | 20464 | 94.1 | 90.0 | 78.5 |
64 | 98568 | 3739 | 170364 | 18864 | 36143 | 90.0 | 82.5 | 72.3 |
all NN | 91452 | 3420 | 155239 | 16206 | 32472 | 90.6 | 82.7 | 65.9 |
TRIBE-MCL | ||||||||
97792 | 6755 | 191500 | 12764 | 16939 | 93.8 | 91.9 | 81.3 | |
gSPC | ||||||||
6 | 79406 | 9543 | 162210 | 6208 | 7709 | 96.3 | 95.5 | 68.8 |
20 | 100458 | 2803 | 201766 | 9634 | 12402 | 95.4 | 94.2 | 86.6 |
64 | 103585 | 427 | 207131 | 10312 | 13264 | 95.3 | 94.0 | 87.9 |
All NN | 103729 | 30 | 207339 | 10362 | 13304 | 95.2 | 94.0 | 88 |