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Table 2 Statistics of interface interactions

From: Oligomeric protein structure networks: insights into protein-protein interactions

Interaction Type6

Nonhub-Nonhub

Hub-Nonhub

Hub-Hub

Imin = 4%

   

Charged+Polar interactions1 (Salt bridges)3,5

34% (11%)

37% (12%)

44% (13.7%)

Hydrophobic interactions2 (Aromatic-Aromatic interactions)4,5

26.5% (3.2%)

24% (5.7%)

22% (9%)

Imin = 0%

   

Charged+Polar interactions (Salt bridges)

35.3% (8%)

24.3% (7%)

21.5% (6%)

Hydrophobic interactions (Aromatic-Aromatic interactions)

23% (0.4%)

32% (1%)

40% (5%)

  1. 1Charged and polar interactions involve Arg, Lys, His, Glu, Asp, Gln, Asn, Ser, Thr, Cys.
  2. 2Hydrophobic and Aromatic interactions involve Leu, Ile, Val, Ala, Gly, Met, Pro, Phe, Tyr and Trp.
  3. 3Salt bridges are between Arg/His/Lys and Glu/Asp.
  4. 4Aromatic interactions involve Phe/Tyr/Trp with themselves.
  5. 5The values given within parentheses are either the salt bridges amongst the charged+polar interactions or the aromatic-aromatic interactions amongst the hydrophobic interactions.
  6. 6The rest of the interactions in each category (adding up to 100%) involve charged/polar versus hydrophobic/aromatic interactions.
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BMC Bioinformatics

ISSN: 1471-2105

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