Table 5 Top ranking genes by Z-score (top 24 genes, this paper), by TNoM score (top 30 genes [13]1), and by differential expression in AML or in ALL (top 25 genes, [14]2). As the Z-score can give genes equal scores, a rank of 1 can be assigned to several genes. In our study 12 genes are ranked 1, in that of [13] 3 are ranked 1. The lowest place in a total ordering of the genes is indicated by figure in parenthesis, e.g. (≤12). Genes ranked in column 5 cannot appear in column 6, and vice versa, as indicated by (-). Otherwise, a blank entry indicates a ranking outside of the top 24, 25 or 30 genes respectively.
Gene | Description | Rank by Z-score | Rank by TNoM1 | Rank in AML2 | Rank in ALL2 |
|---|---|---|---|---|---|
M23197 | Myeloid cell surface antigen CD33 | 1 (≤12) | 1 (≤3) | 22 (≤22) | - |
X04145 | T-cell surface glycoprotein CD3 | 1 (≤12) | |||
M31211 | Myosin light chain | 1 (≤12) | 6 (≤20) | - | 4 (≤4) |
M31303 | Leukemia-associated phosphoprotein | 2 (≤13) | 7 (≤32) | - | 11 (≤13) |
U50136 | Leukotriene C4 | 3 (≤24) | 7 (≤32) | 3 (≤3) | - |
M28170 | B-lymphocyte surface antigen CD19 | 3 (≤24) | |||
J04132 | T-cell surface glycoprotein CD3 | 3 (≤24) | |||
X95735 | Zyxin | 1 (≤3) | 6 (≤6) | - | |
M55150 | Fumarylacetoacetate | 6 (≤20) | 1 (≤1) | - | |
X59417 | Proteasome iota chain | 6 (≤20) | - | 3 (≤3) | |
U22376 | C-myb | - | 1 (≤1) |