Figure 6From: Visualization-based discovery and analysis of genomic aberrations in microarray dataPredicted amplifications and deletions on breast cancer array CGH data. ChARMView automated predictions on three breast tumor array CGH profiles (110B, 112B, 122A) from chromosome 1 and three profiles (123B, 309A, and BC-A) from chromosome 17 of [18]. The predicted chromosome 1 breakpoints (identified by arrows in Figure 6A) are 3, 1, and 0 probes from the centromere. The predicted chromosome 17 amplification common to all three profiles (identified by arrows in Figure 6B) includes 7 genes known to be typically amplified with the ERBB2 locus. All visible predictions have Bonferroni-corrected p-values less than .05 for both mean and sign significance tests. See Table 2 for a complete list of breakpoint predictions for each of the results pictured.Back to article page