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Figure 6 | BMC Bioinformatics

Figure 6

From: Visualization-based discovery and analysis of genomic aberrations in microarray data

Figure 6

Predicted amplifications and deletions on breast cancer array CGH data. ChARMView automated predictions on three breast tumor array CGH profiles (110B, 112B, 122A) from chromosome 1 and three profiles (123B, 309A, and BC-A) from chromosome 17 of [18]. The predicted chromosome 1 breakpoints (identified by arrows in Figure 6A) are 3, 1, and 0 probes from the centromere. The predicted chromosome 17 amplification common to all three profiles (identified by arrows in Figure 6B) includes 7 genes known to be typically amplified with the ERBB2 locus. All visible predictions have Bonferroni-corrected p-values less than .05 for both mean and sign significance tests. See Table 2 for a complete list of breakpoint predictions for each of the results pictured.

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