Table 3 Comparison of PAGE results from data sets produced using different microarray platforms
U95A | U133A | Agilent | ||||||
|---|---|---|---|---|---|---|---|---|
Gene Set | Z score | p-value | Gene Set | Z score | p-value | Gene Set | Z score | p-value |
Complement Activation Classical | 3.0477 | 0.0023 | Krebs TCA Cycle | 5.0505 | 4.41E-07 | tRNA Synthetases | 3.1714 | 0.0015 |
Krebs-TCA Cycle | 2.6771 | 0.0074 | Cell Cycle | 3.4088 | 0.0007 | Krebs TCA Cycle | 3.1291 | 0.0018 |
Nuclear Receptors | 2.6562 | 0.0079 | Translation Factors | 2.8213 | 0.0048 | Proteasome Degradation | 1.9894 | 0.0467 |
Calcium Channels | 1.6956 | 0.0900 | Nuclear Receptors | 2.3404 | 0.0193 | Glycolysis and Gluconeogenesis | 1.5679 | 0.1169 |
Apoptosis | 1.4085 | 0.1590 | Complement Activation Classical | 2.2861 | 0.0223 | Steroid Biosynthesis | 1.5109 | 0.1308 |
TGF Beta Signaling Pathway | -1.8580 | 0.0632 | Matrix Metalloproteinases | -2.2837 | 0.0224 | Ribosomal Proteins | -2.1275 | 0.0334 |
Inflammatory Response Pathway | -2.2590 | 0.0239 | TGF Beta Signaling Pathway | -3.3762 | 0.0007 | Glycogen Metabolism | -2.4904 | 0.0128 |
Glycogen Metabolism | -2.6981 | 0.0070 | Inflammatory Response Pathway | -3.5668 | 0.0004 | TGF Beta Signaling Pathway | -2.6910 | 0.0071 |
Cholesterol Biosynthesis | -4.6988 | 2.62E-06 | Cholesterol Biosynthesis | -5.8165 | 6.01E-09 | Cholesterol Biosynthesis | -4.1642 | 3.12E-05 |
Gap Junction Proteins-Connexins | -5.7792 | 7.51E-09 | Gap Junction Proteins-Connexins | -6.2689 | 3.64E-10 | Gap Junction Proteins-Connexins | -6.6162 | 3.69E-11 |