Transcription Factor | Genomewide | B+/C+ | B+/C- |
---|
 |
Mean
|
SD
|
Mean
|
SD
|
-log
10
(p)
|
Mean
|
SD
|
-log
10
(p)
|
Dig1 | 0.759 | 0.198 | 0.567 | 0.360 | 3.76 | 0.846 | 0.080 | 0.04 |
Gcn4 | 0.785 | 0.177 | 0.294 | 0.329 | 28.23 | 0.793 | 0.170 | 0.24 |
Hir2 | 0.724 | 0.218 | 0.180 | 0.295 | 4.00 | 0.760 | 0.194 | 0.14 |
Mbp1 | 0.830 | 0.121 | 0.541 | 0.324 | 27.86 | 0.770 | 0.172 | 2.79 |
Swi4 | 0.524 | 0.338 | 0.348 | 0.352 | 4.89 | 0.533 | 0.333 | 0.24 |
Swi5 | 0.744 | 0.204 | 0.583 | 0.373 | 5.98 | 0.759 | 0.186 | 0.17 |
Yap1 | 0.756 | 0.201 | 0.471 | 0.376 | 7.66 | 0.587 | 0.337 | 2.67 |
- The mean and the standard deviation of gene expression log-ratio between mutant and wild type as obtained in Hughes et al. were calculated for all genes in the genome as well as for the B+/C+ and B+/C- groups [21]. A sample t-test was performed to determine the significance of the change in expression. The B+/C+ genes show a significant change in mRNA expression for the 7 transcription factors for which deletion and ChIP data is available. By contrast, the response of the B+/C- genes is insignificant for most transcription factors.