Table 4 The numbers of homologous enzyme pairs and enzyme pairs found at MPLs 1–12. The fraction is simply the ratio between the number of homologous enzyme pairs and the enzyme pairs. The reduced network is the network where the 20 most promiscuous compounds have been removed.
From: Network analysis of metabolic enzyme evolution in Escherichia coli
| Â | WHOLE NETWORK | REDUCED NETWORK | ||||
|---|---|---|---|---|---|---|
MPL | HOMOLOGS | ENZYME PAIRS | FRACTION | HOMOLOGS | ENZYME PAIRS | FRACTION |
1 | 4.662 | 121,295 | 0.0384 | 429 | 6,035 | 0.071 |
2 | 2,982 | 452,081 | 0.0066 | 561 | 33,203 | 0.017 |
3 | 340 | 67,857 | 0.0050 | 1,115 | 105,254 | 0,011 |
4 | 5 | 2,861 | 0.0017 | 1,472 | 146,932 | 0.010 |
5 | 0 | 553 | 0 | 1,188 | 99,240 | 0.012 |
6 | 0 | 9 | 0 | 611 | 47,115 | 0.013 |
7 | - | - | - | 265 | 18,975 | 0.014 |
8 | - | - | - | 97 | 5,707 | 0.017 |
9 | - | - | - | 25 | 1,217 | 0.021 |
10 | - | - | - | 9 | 230 | 0.039 |
11 | - | - | - | 1 | 17 | 0.059 |
12 | - | - | - | 0 | 2 | 0 |
Total | 7.989 | 644,656 | 0.0124 | 5,773 | 463,927 | 0.013 |