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Figure 3 | BMC Bioinformatics

Figure 3

From: Statistical significance for hierarchical clustering in genetic association and microarray expression studies

Figure 3

Results from log-rank tests applied to steps of the hierarchical structure formed by clustering data from Alizadeh et al. [12]. A, This schematized dendrogram reflects the process of clustering microarray samples according to the similarity of their gene expression profiles as measured by the Pearson correlation coefficient. Distances between array sample clusters are approximated (not to scale) by the vertical axis. Along the bottom of the dendrogram are the microarray tissue samples from individuals for which survival data was available [12]. B, This bar graph displays the local p-values we compute at each step within the structure created by hierarchical clustering.

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