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Table 1 The runtimes of the four algorithms on the same simulated dataset.

From: Identifying overlapping mutated driver pathways by constructing gene networks in cancer

 

Average runtime (seconds)

q

Iterative-RME

Iterative-Dendrix

Multi-Dendrix

NBM

0.0001

30.26

635.68

5.32

7.25

0.0005

42.37

685.35

7.03

7.56

0.001

165.28

645.87

8.35

7.89

0.005

N/A

721.32

9.56

7.86

0.01

N/A

756.48

11.48

8.35

0.015

N/A

786.69

13.98

8.43

0.02

N/A

843.53

15.45

8.58

  1. A comparison of the runtimes of Iterative-RME, Iterative-Dendrix, Multi-Dendrix and NBM on simulated mutation data with different passenger mutation probability q. Runtimes of each algorithm are shown as the mean of 20 runs for each q. N/A represents that Iterative-RME algorithm does not give any result within 24 hours. Simulations are performed on the machine running 64-bit windows with Intel Xeon 2.0 GHz processor and a maximum of 6 GB of available memory.